Best Medicine Season 2 Episode 4 Preview: Promo, Photos, and Air Date

Martin can’t seem to catch a break in the promo for Fox’s Best Medicine season two, episode four. Episode four, “No Place Like Om,” will air on Tuesday, October 13, 2026 at 8pm ET/PT.

“No Place Like Om” Plot: As Martin desperately tries to leave Port Wenn to meet Eden in Boston for the weekend, he must first investigate the extremely strange behavior of three patients who have all recently visited a meditation retreat. Also, Mark is affected by the high school’s graduation and Sarah’s first guest in her rented spare room is none other than ex-paramour Eddie McCroy.

Josh Charles stars as Dr. Martin Best, Abigail Spencer is back as Louisa Gavin, Josh Segarra reprises his role as Sheriff Mark Mylow, Annie Potts stars as Aunt Sarah, and Cree returns as Elaine Denton. Stephen Spinella plays Greg Garrison and Jason Veasey plays George Brady.

Best Medicine Plot, Courtesy of Fox:

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin’s blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he’s all they’ve got.

Although Martin can expertly address any medical ailment or mystery in this idiosyncratic town, he’s really just desperate to be left the hell alone. Instead, he keeps getting dragged right smack into the middle of their personal chaos, feuds, and fantasies. What the locals don’t know is that Martin’s terse demeanor masks a debilitating new phobia and deep-seated psychological issues that prevent him from experiencing true intimacy with anyone. But tenacity is the creed of everyone in their small village, and the people who live there may be exactly what the doctor ordered.

• Season 2 Episode 1 “Be Careful What You Wish For” Preview
• Season 2 Episode 2 “Breakin’ In Is Hard to Do” Preview
• Season 2 Episode 3 “Crate Expectations” Preview