Fox’s Doc will be taking a two-week break due to the 2025 World Series between the Los Angeles Dodgers and the Toronto Blue Jays. The popular medical drama returns with season two, episode six on Tuesday, November 4, 2025 at 9pm ET/PT.
Molly Parker stars as Dr. Amy Larsen, Omar Metwally plays Dr. Michael Hamda, Felicity Huffman is Dr. Joan Ridley, Amirah Vann is Dr. Gina Walker, and Charlotte Fountain-Jardim plays Katie Hamda. Jon Ecker is Dr. Jake Heller and Anya Banerjee plays Dr. Sonya Maitra.
“Saints and Sinners” Plot: Amy treats a chaplain who helps her reconcile with the past, while Michael is under investigation for his actions during the hostage crisis. Also, TJ returns to work and treats a prisoner and Hannah’s brother shows up with a plan.
Doc Series Description, Courtesy of Fox:
“Inspired by a true story and based on the hit eponymous Italian drama series, Doc begins its second season of the life-affirming medical drama following the heartbreak and victories of hard-charging, brilliant physician DR. AMY LARSEN (Parker) as she rebuilds her life after a car crash erased eight years of her memory. This season, Amy will continue to confront hard truths about her missing years, work to repair fractured relationships and seek to reconcile the person she used to be with the one everyone else has come to know.
Determined to get her memory back and piece together who she really is, Amy’s goal is to become the doctor she used to be in those missing years and to eventually, once again, be Chief of Internal Medicine. In the interim, her ex-husband/Westside Hospital’s Chief Medical Officer, DR. MICHAEL HAMDA (Metwally) fills the position with Amy’s former mentor and friend DR. JOAN RIDLEY (Huffman), whose motives and priorities remain hidden, just as long as Amy still can’t recall Joan’s life-changing secret. Amy’s best friend and colleague, DR. GINA WALKER (Vann), is weary of Joan’s motives and continues to be a beacon of support for those around her, while finally learning to put on her own oxygen mask first.
While relearning eight years of medical advancements is complicated, it pales in comparison to learning to navigate her new/old/current romantic entanglements. Amy continues to fight her feelings and let Michael go, especially now with the birth of his son with his new wife, bringing up emotions for both Amy and their daughter KATIE HAMDA (Fountain-Jardim). Amy’s on-again, off-again relationship with Chief Resident DR. JAKE HELLER (Ecker) is a bit more delicate as he struggles to protect his heart from her this time around. However, DR. SONYA MAITRA (Banerjee) would only be too glad to pick up the pieces, navigating the balance between her feelings for Jake and her complicated resentment towards Amy.
The second season of Doc begins as Amy’s past comes back to haunt her when a desperate father sacrifices everything to secure his daughter’s heart transplant. Chaos and confusion reverberate through the hallways of Westside Medical when a subsequent high-stakes emergency leaves a doctor’s life in the balance.”
- Season 2 Episode 1 “Her Heart” Preview
- Season 2 Episode 2 “Delusions of Grandeur” Preview
- Season 2 Episode 4 “Something to Prove” Preview
- Season 2 Episode 5 “Tightrope” Preview
- Season 2 Episode 7 “What I Did for Love” Preview
- Season 2 Episode 8 “He Loved You” Preview
- Season 2 Episode 9 “Kaddish” Preview
- Season 2 Episode 10 “Chief” Preview
- Season 2 Episode 11 “Family Matters” Preview
- Season 2 Episode 12 “Inquisition” Preview
- Season 2 Episode 14 “When You Know, You Know” Preview
This post was last modified on January 29, 2026 3:09 pm